Job description


  • Entry level
  • No Education
  • Salary to negotiate
  • London


Research Programme

The research programme of the Reprogramming and Chromatin group led by Prof Petra Hajkova focuses on investigation of molecular mechanisms underlying epigenetic reprogramming in vivo and in vitro (for further information, please visit (

Purpose of Post

Is to investigate the molecular principles of developmental reprogramming.

The candidate will be expected to carry out research within the focus area of the Reprogramming and Chromatin Group; undertake project management and be involved in the supervision of PhD students in the laboratory. In addition, he/she will be expected to submit publications to refereed journals and to attract external research funding.

Main duties / key responsibilities:

To take initiatives in the planning of research

To direct the work of small research teams

To identify and develop suitable techniques, and apparatus, for the collection and analysis of data

To conduct data analysis

To ensure the validity and reliability of data at all times

To maintain accurate and complete records of all findings

To write reports for submission to research sponsors

To present findings to colleagues and at conferences

To submit publications to refereed journals

To provide guidance to staff and students

To attend relevant workshops and conferences as necessary

To develop contacts and research collaborations within the College and the wider community

To promote the reputation of the Group, the Department and the Institute

To provide guidance to PhD Students

Contribute to bids for research grants

To conduct and plan own scientific work with appropriate supervision

To maintain highly organised and accurate record of experimental Work.

To actively participate in the research programme of the Group and Unit

To publish in high quality journals and to present data at national and international meetings

To participate in Group/Unit research meetings and internal seminars.

Willingness to work out of normal working hours (including weekends) if the requirements of the project demand

To collaborate with other allied scientists within Institute and elsewhere in London and abroad, as appropriate

To contribute to the smooth running of the Group’s/Unit’s laboratories and, facilities with other scientists, clinicians, technicians and students within the laboratories

To assist in the supervision of undergraduate and postgraduate research students and research assistants as required

To comply with the Institute safety practices and to attend courses on safety when appropriate

Any other duties as may be deemed reasonable by Head of group

This post is a MRC Postdoctoral Research Scientist to support post-doctoral training and help establish successful research scientists in their chosen field. During the fellowship tenure we are committed to provide mentorship for career development and improvement of communication skills. We also offer a highly attractive benefits package including competitive salary and salary pension scheme. It is initially a 2-year training and development post, which incorporates both scientific and transferable skills training.

Person Specification

Education / Qualifications / Training required (will be assessed from the application):


PhD degree in a biological or related discipline or the equivalent experience


UK Home Office personal licence (PIL) for work with rodents

Previous work experience required (will be assessed from the application and at the interview):


Proven experience in the field of epigenetics and chromatin.

Experience with immunofluorescence techniques and confocal imaging

Extensive experience with mouse ES cells culture techniques

Extensive experience with immunohistochemistry, paraffin- and cryosections

Knowledge of relevant biochemical and molecular biology research methods and statistical procedures


Extensive experience with early mouse embryo culture and manipulation

Experience with the use of imaging software would be advantageous

Personal skills/behaviours/qualities (will be assessed at the interview):


Evidence of organisational ability

Good written and verbal communication skills and the ability to work effectively with researchers ranging from postgraduate students to professorial level

Ability to work both independently and as part of a team

IT literate and familiar with basic methods for sequence and image analysis

A highly committed individual with proactive and flexible attitude to work

The ability and willingness to learn new concepts and technologies rapidly

The ability to work under pressure in the competitive field

Further Information

Please upload your CV, names and contacts of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Please quote reference number LMS – 1082.

- Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two.

The MRC is a great place to work and progress your career, be it in scientific research or the support functions.The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.

Choosing to come to work at the MRC (part of UKRI) means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.

Our success is dependent upon our ability to embrace diversity and draw on the skills, understanding and experience of all our people. We welcome applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age. As "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.

UKRI supports research in areas that include animal health, agriculture and food security, and bioscience for health which includes research on animals, genetic modification and stem cell research. Whilst you may not have direct involvement in this type of research, you should consider whether this conflicts with your personal values or beliefs.

We will conduct a full and comprehensive pre-employment check as an essential part of the recruitment process on all individuals that are offered a position with UKRI. This will include a security check and an extreme organisations affiliation check.