Job description

Requirements

  • Entry level
  • No Education
  • Salary to negotiate
  • Thousand Oaks

Description

The Pre-Pivotal Drug Substance Technologies organization at Amgen develops, characterizes, and supports clinical drug substance manufacturing processes for all early-stage programs in the Amgen portfolio.

This lab-based position is located at our Thousand Oaks, CA site. The successful candidate will be responsible for support of the development, characterization, scale-up and support of upstream and downstream processes to enable clinical advancement of Amgen programs.

This role is in an integrated bioprocess development group in which cell culture and purification scientists work together to advance Amgen’s rich, exciting and dynamic pipeline. With Amgen’s biology first approach, the position provides the unique opportunity to work on multiple modalities including antibodies, BiTEs, oncolytic viruses, bispecifics, and siRNAs.

The successful candidate will design and execute experiments at the bench scale, spanning the end-to-end drug substance process, including both cell culture and purification operations. The candidate will apply established platform approaches and utilize problem-solving skills to rapidly solve day-to-day experimental challenges. Additionally, the candidate will utilize out-of-the-box thinking to contribute to technology development. Finally, the candidate will also expand and develop skills in both cell culture and purification, thereby further contributing to the integrated group.

Basic Qualifications:

Master’s degree

OR

Bachelor’s degree with two years of scientific experience

OR

Associate degree with 4 years of scientific experience

Preferred Qualifications:

Master’s degree in Chemical Engineering, Biochemical Engineering, Life Sciences, or other relevant sciences with a demonstrated record of excellence.

Ability to identify, develop and implement solutions to practical problems through application of fundamental scientific and engineering principles, preferably in a process development environment.

Basic understanding of protein chromatography, filtration or cell culture principles; hands-on experience with mammalian cell culture, and/or purification operations is a plus.

Prior experience with data analytical tools (Excel, Spotfire, etc.) is preferred. Experience with statistical analysis and programming in JMP, R, and/or Python environments is a plus.

Motivated self-starter with excellent interpersonal and organizational skills.

Team player with the ability to successfully work within a diverse team in a dynamic, cross-functional environment.

Familiarity with design of experiments and statistical analysis of data desirable.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

About the company

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

For more information, visit www.amgen.com and follow us on www.twitter.com/amgen.

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