Job description


  • Entry level
  • No Education
  • Salary to negotiate
  • Ohio


Job Title: Research Assistant 2
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8081
Salary Grade
Salary Grade 10 for staff working 40 hours per week
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Working under general supervision, the Research Assistant will plan and carry out research projects involving standard molecular techniques (PCR, electrophoresis, RNA extraction), immunological techniques (ELISA, flow-cytometry, western blotting), animal handling, record-keeping of mouse breeding, tissue processing (immunohistochemistry) and tissue-culturing/cell culture work. The Research Assistant will also collect, verify, record, compile and analyze data and information related to the ongoing research carried out in the lab. This position will oversee inventory and general lab maintenance. This position will work with animals.


- Plan and carry out research projects. Perform procedures and operate a variety of instruments and scientific equipment, i.e. microscopy, PCR, gel electrophoresis, histology, biochemical assays and others. Collect and analyze data and results to lab. (25%)
- Conduct series of experiments to supply scientific information to the lab. Analyze samples and maintain cell/ tissue cultures for experimental purposes and analyzing animal tissues. (25%)
- Assist with developing techniques and procedures in regards to animal studies (mouse). This includes diet manipulation, drug administration, simple cardiovascular disease model surgeries, organ isolation and taking care of animals. Oversee inventory and general maintenance. (25%)
- Maintain animal breeding colonies of transgenic animals. Perform data entry and maintain accurate records for genotyping in close coordination with the required lab personnel. (10%)


- Train new staff and/or students within their own area of expertise or their own line of research work. (5%)
- Perform other duties as assigned to ensure contribution to research results on an ongoing basis. (5%)


Department: Daily contact with principle investigator/supervisor and other laboratory personnel to discuss results and plans for maintaining colonies.

University: Occasional contact with other departments to share information.

External: Limited or no contact with vendors to exchange information.

Students: Contact with student employees to provide training or instruction.


This position has no direct supervision of staff employees.


Education and Experience: Bachelor's degree and 1 to 3 years of related experience or Associate's degree in an approved biotechnology program and 2 to 4 years of experience.


- Understanding of working with mouse models as well as heart and immune models preferred.
- Understanding of aseptic working practices.
- Ability to perform tissue processing for histology (cryo- and paraffin-block sectioning) and histochemical staining, including immunohistochemistry and immunofluorescence.
- Ability to perform basic molecular biology and biochemistry techniques. (PCR, molecular cloning, DNA and RNA isolation, RT-PCR, qPCR, ChIP, Western blotting, etc).
- Good organizational skills and record keeping.
- Ability to follow strict safety guidelines.
- Ability to meet consistent attendance.
- Ability to interact with colleagues, supervisors and customers face-to-face.
- Ability to follow through on assigned projects and provide timely follow-up.
- Ability to work in a fast-paced, changing environment, and conform to shifting priorities, demands, and timeline. Must be flexible in order to respond to project adjustments and alterations promptly and efficiently. Must be able to adapt to varying workloads and respond appropriately to stressful situations.
- Excellent verbal and written communication skills. Good interpersonal skills; ability to work and communicate professionally with various individuals within the laboratory and department.
- Must demonstrate compliance with CWRU animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.
- Must demonstrate compassion for animals within CWRU facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.
- Previous experience working with animals preferred.


Typical laboratory environment. Personal laboratory safety devices will be provided. The employee will be exposed to animals and chemicals, UV light, fumes, dust.

Case's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.

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In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


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Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.


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