Job description


  • Entry level
  • No Education
  • Salary to negotiate
  • Philadelphia


Job location: Translational Research Laboratories

Employment Type: Full-time
Posted data: 2019-12-03
Req: JR00013837
University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title

Research Specialist D, Immunlogy

Job Profile Title

Research Specialist D

Job Description Summary

The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine, as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases. GTP is a complex R&D organization consisting of research laboratories supported by multiple core functions which provide internal capacity to perform gene transfer studies from basic research through Phase 1 proof-of-concept human trials.

The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the ‘go-to’ organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.

Job Description

Due to continued growth of our program, the Immunology Core is in search of a Research Specialist D to assist in enhancing data output and laboratory compliance.

As a Research Specialist D working in a highly regulated Good Laboratory Practices (GLP) environment, this individual will perform experiments related to the analyses of T and B cell immune responses with limited supervision. Studies of interest will cover a large range of research areas from basic discovery research to IND enabling studies to Phase 1 Clinical Trials. More specifically, these studies will involve the isolation of lymphocytes from blood and tissues, immunological B cells assays such as viral vector neutralizing antibody assays and T-cell assays such as IFN-γ ELISPOT. Additional duties of this position involve validation of GLP grade assays, regents and equipment as well as the generation and reporting of data to Core Management. A successful candidate will also be expected to write and review Immunology Core specific Standard Operating Procedures (SOPs). This position involves interaction with other Gene Therapy Program units; particularly GTP’s Quality Assurance Unit to ensure sample management; data collection and equipment maintenance are consistently performed under GLP. This individual will also be called upon to mentor and train new members of the Core on relevant experimental techniques and SOPs.


Master's Degree with 3-5 years of related experience of progressive experience, preferably in a GLP environment or an equivalent combination of education and relevant experience is required. The candidate shall also have complete familiarity with relevant immunological assays used by the core in pre-clinical testing as well as clinical trials. The candidate must be well versed with Good Laboratory Practices (GLP) and procedures for the proper handling of biological materials in a laboratory setting.

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$50,684.00 - $91,232.00

Affirmative Action Statement
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

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