Job description


  • Entry level
  • No Education
  • Salary to negotiate
  • South San Francisco


Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist in Discovery Chemistry, for our site in South San Francisco, CA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information.

We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

The newly formed Discovery Chemistry group is committed to the delivery of high quality drug candidates working with all six Janssen Therapeutic Areas (TA) discovery teams. This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, enzymology, and screening technologies coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as Senior Scientist, Discovery Chemistry. This position will be based at our drug discovery site in South San Francisco, CA.

We are seeking an experienced medicinal chemist with excellent organic synthesis expertise to advance small molecule drug discovery programs toward the clinic. The successful candidate will partner with the internal medicinal chemistry team to generate innovative solutions to synthetic and medicinal chemistry challenges within the context of small molecule drug discovery. A practical knowledge of modern drug design, the application of chemoinformatics tools and experience advancing small molecule inhibitors of PPI targets towards the clinic would be advantageous. This individual must also excel in communication and have strong interpersonal skills necessary to influence in a collaborative multidisciplinary environment, and ideally have some leadership experience.

• Maintain a high level of productivity in the laboratory setting.
• Develop and execute clear synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies.
• Independently design and synthesize drug-like molecules utilizing medicinal chemistry knowledge and an understanding of ADME, pharmacokinetics and optimal physicochemical properties.
• Collaboratively support the advancement of compounds through in vitro and in vivo studies to identify development candidates.
• Collaborate with structure-based design groups to impact rational design of molecules.
• Generate novel, testable hypotheses to enable clear decision making.
• Manage external synthesis support.
• Contribute to defining scientific strategies and goals within a project team setting.
• Present data and reports on project status at individual, group, departmental and organizational meetings.
• Draft, execute and serve as lead author on research published in peer reviewed journals and present work at scientific conferences.
• Collaboratively engage with the external scientific community.
• Present data and reports on project status at individual, group, departmental and organizational meetings.

• A Ph.D. in synthetic organic chemistry or related with atleast 3 or more years of relevant scientific experience in Medicinal Chemistry is required OR
• Or a Master’s degree with at least 12 or more years of experience
• Or a Bachelor’s degree with at least 15 or more years of experience
• Postdoctoral experience is preferred.
• Pharmaceutical Industry experience preferred.
• Demonstrate a strong track record of achievement in synthesis of complex molecules with knowledge of modern synthetic, analytical techniques.
• Proven track record of scientific contributions including peer reviewed publications, patents and/or presentations is required.
• Demonstrate

About the company

If you’re thinking about taking your career to a place where you can be seen for the talent you bring to your work, where you’ll have a chance to be the driver of your own career, and where others share your passion for caring and success, then we invite you to explore Johnson & Johnson. BE VITAL in your career and make a unique mark. Join the approximately 129,000 men and women who work within our companies and touch the lives of more than a billion people around the world every day.

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